Phase diagram determination for phospholipid/sterol membranes using deuterium NMR

Ya Wei Hsueh; Martin Zuckermann; Jenifer Thewalt

doi:10.1002/cmr.a.20034

Phase diagram determination for phospholipid/sterol membranes using deuterium NMR

Ya Wei Hsueh, Martin Zuckermann, Jenifer Thewalt

Department of Physics

Research output: Contribution to journal › Article › peer-review

16 Scopus citations

Abstract

Deuterium NMR is used to investigate the phase behavior of membranes containing ergosterol and to measure the temperature-ergosterol mole fraction phase diagram. In particular, our approach to analyzing the NMR spectra has allowed us to definitively locate and characterize the region where two liquid crystalline phases coexist. The general methodology for phase boundary determination in phospholipid/sterol membranes is presented.

Original language	English
Pages (from-to)	35-46
Number of pages	12
Journal	Concepts in Magnetic Resonance Part A: Bridging Education and Research
Volume	26
Issue number	1
DOIs	https://doi.org/10.1002/cmr.a.20034
State	Published - May 2005

Keywords

H NMR
Ergosterol
Phase diagram
Phosphatidylcholine

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10.1002/cmr.a.20034

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AU - Zuckermann, Martin

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AB - Deuterium NMR is used to investigate the phase behavior of membranes containing ergosterol and to measure the temperature-ergosterol mole fraction phase diagram. In particular, our approach to analyzing the NMR spectra has allowed us to definitively locate and characterize the region where two liquid crystalline phases coexist. The general methodology for phase boundary determination in phospholipid/sterol membranes is presented.

KW - H NMR

KW - Ergosterol

KW - Phase diagram

KW - Phosphatidylcholine

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M3 - 期刊論文

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Phase diagram determination for phospholipid/sterol membranes using deuterium NMR

Abstract

Keywords

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