Optical resolution of amino acid by ultrafiltration through immobilized DNA membranes

Akon Higuchi, Kentaro Furuta, Hiroshi Yomogita, Boo Ok Yoon, Mariko Hara, Syunji Maniwa, Masatoshi Saitoh

Research output: Contribution to journalArticlepeer-review

16 Scopus citations

Abstract

Ultrafiltration experiments for the optical resolution of racemic phenylalanine were investigated in a DNA solution system and by using immobilized DNA membranes. L-phenylalanine preferentially existed in the permeate solution and D-phenylalanine preferentially existed in the concentrate solution in the ultrafiltration of racemic phenylalanine through the immobilized DNA membranes. This indicates that L-phenylalanine preferentially enters into the pores of the immobilized DNA membranes and permeates through the membranes due to the interaction between DNA and L-phenylalanine. The immobilized DNA membranes were categorized as channel type membranes.

Original languageEnglish
Pages (from-to)155-157
Number of pages3
JournalDesalination
Volume148
Issue number1-3
DOIs
StatePublished - 10 Sep 2002

Keywords

  • Channel
  • Chiral separation
  • DNA
  • Optical resolution
  • Ultrafiltration

Fingerprint

Dive into the research topics of 'Optical resolution of amino acid by ultrafiltration through immobilized DNA membranes'. Together they form a unique fingerprint.

Cite this