Novel zwitterionic nanocomposite hydrogel as effective chronic wound healing dressings

Kang Ting Huang, Chun Jen Huang

Research output: Chapter in Book/Report/Conference proceedingConference contributionpeer-review

2 Scopus citations

Abstract

We have synthesized and characterized a novel zwitterionic nanocomposite hydrogel as effective chronic wound healing dressings. The hydrogel is composited of nonfouling zwitterionic polymer as a major composition, plus small quantity of nano-sized clay for improved mechanical strength and in-situ formation silver nanoparticles for antimicrobial function. The novel zwitterionic nanocomposite hydrogel possesses unique features, including 1. biocmpatibility; 2. high water content; 3. anti-biofouling properties; 4. strong durability; 5. suppression of bacterial growth; 6. controlled release of Ag ions. These features allow developed formulation becoming extraordinary chronic wound dressing for clinical applications.The hydrogel was fabricated via a “onepot synthesis” approach and the physicochemical properties were characterized detail. Moreover, the antifouling properties of hydrogels were evaluated in contact with a protein and bacterial solutions.

Original languageEnglish
Title of host publication1st Global Conference on Biomedical Engineering and 9th Asian-Pacific Conference on Medical and Biological Engineering
EditorsFong-Chin Su, Ming-Long Yeh, Shyh-Hau Wang
PublisherSpringer Verlag
Pages35-38
Number of pages4
ISBN (Electronic)9783319122618
DOIs
StatePublished - 2015
Event1st Global Conference on Biomedical Engineering, GCBME 2014 and 9th Asian-Pacific Conference on Medical and Biological Engineering, APCMBE 2014 - Tainan, Taiwan
Duration: 9 Oct 201412 Oct 2014

Publication series

NameIFMBE Proceedings
Volume47
ISSN (Print)1680-0737
ISSN (Electronic)1433-9277

Conference

Conference1st Global Conference on Biomedical Engineering, GCBME 2014 and 9th Asian-Pacific Conference on Medical and Biological Engineering, APCMBE 2014
Country/TerritoryTaiwan
CityTainan
Period9/10/1412/10/14

Keywords

  • Antifouing properties
  • Chronic wound healing dressings
  • Silver nanoparticles
  • Zwitterionic hydrogel

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