Nasopharyngeal cancer cell death induced by high-dose gold nanoparticles

Ming Ying Lan, Yen Bin Hsu, Jin Ching Lin, Ching Yin Ho, Sheng Wei Lee

Research output: Chapter in Book/Report/Conference proceedingConference contributionpeer-review


This study investigated if gold nanoparticles (AuNPs) could be used as a new therapeutic agent for NPC by evaluating their anti-tumor effect in vitro. AuNPs prepared in this study had an average diameter of 20.5 nm and they were observed under light microscopy as dark material aggregated in the cells after treatment. The AuNPs reduced cell viability in a concentration-dependant manner by Trypan Blue assay: 74.7% at 50 μM, 39.0% at 100μM, and 7.1% at 200 μM, respectively. TUNEL stain was positive in AuNP-treated cells. The AuNP possess specific imaging properties and is cytotoxic to NPC cells at high concentrations.

Original languageEnglish
Title of host publication4th IEEE International NanoElectronics Conference, INEC 2011
StatePublished - 2011
Event4th IEEE International Nanoelectronics Conference, INEC 2011 - Tao-Yuan, Taiwan
Duration: 21 Jun 201124 Jun 2011

Publication series

NameProceedings - International NanoElectronics Conference, INEC
ISSN (Print)2159-3523


Conference4th IEEE International Nanoelectronics Conference, INEC 2011


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