Multiple comparisons between successive treatments for randomly right-censored survival data

Yuh Ing Chen; Yunchan Chi

doi:10.1016/s0378-3758(99)00050-6

Multiple comparisons between successive treatments for randomly right-censored survival data

Yuh Ing Chen, Yunchan Chi

Graduate Institute of Statistics

Research output: Contribution to journal › Article › peer-review

1 Scopus citations

Abstract

In this paper we are concerned with the problem of comparing adjacent ordered treatments in a one-way layout where survival data are subject to random right censorship. Multiple testing procedures based on two-sample statistics, each comparing an individual treatment with the previous one, are proposed for determining the pattern of the treatment effects. The two-sample statistics under consideration are weighted logrank statistics (Fleming and Harrington, 1991, Counting Process and Survival Analysis. Wiley, New York) and weighted Kaplan-Meier statistics (Pepe and Fleming, 1989. Biometrics 45, 497-507; 1991. J. Roy. Statist. Soc. B 53, 341-352). An illustrated numerical example is reported. Finally, the comparative results of a Monte Carlo error rate and power study for small sample sizes are presented.

Original language	English
Pages (from-to)	137-151
Number of pages	15
Journal	Journal of Statistical Planning and Inference
Volume	83
Issue number	1
DOIs	https://doi.org/10.1016/s0378-3758(99)00050-6
State	Published - 1 Jan 2000

Keywords

62J15
62N05
Monte Carlo study
Multiple comparisons
One-way layout
Right-censored data

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10.1016/s0378-3758(99)00050-6

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title = "Multiple comparisons between successive treatments for randomly right-censored survival data",

abstract = "In this paper we are concerned with the problem of comparing adjacent ordered treatments in a one-way layout where survival data are subject to random right censorship. Multiple testing procedures based on two-sample statistics, each comparing an individual treatment with the previous one, are proposed for determining the pattern of the treatment effects. The two-sample statistics under consideration are weighted logrank statistics (Fleming and Harrington, 1991, Counting Process and Survival Analysis. Wiley, New York) and weighted Kaplan-Meier statistics (Pepe and Fleming, 1989. Biometrics 45, 497-507; 1991. J. Roy. Statist. Soc. B 53, 341-352). An illustrated numerical example is reported. Finally, the comparative results of a Monte Carlo error rate and power study for small sample sizes are presented.",

keywords = "62J15, 62N05, Monte Carlo study, Multiple comparisons, One-way layout, Right-censored data",

author = "Chen, {Yuh Ing} and Yunchan Chi",

note = "Funding Information: The work of the first author was partially supported by the National Science Council of Taiwan under Grant NSC86-2115-M-008-018. We would like to thank the editor and two referees for many helpful suggestions which improve the presentation in this paper. We would also like to thank Mr. Min-Shiao Tsai for his computing assistance. ",

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AU - Chen, Yuh Ing

AU - Chi, Yunchan

N1 - Funding Information: The work of the first author was partially supported by the National Science Council of Taiwan under Grant NSC86-2115-M-008-018. We would like to thank the editor and two referees for many helpful suggestions which improve the presentation in this paper. We would also like to thank Mr. Min-Shiao Tsai for his computing assistance.

PY - 2000/1/1

Y1 - 2000/1/1

N2 - In this paper we are concerned with the problem of comparing adjacent ordered treatments in a one-way layout where survival data are subject to random right censorship. Multiple testing procedures based on two-sample statistics, each comparing an individual treatment with the previous one, are proposed for determining the pattern of the treatment effects. The two-sample statistics under consideration are weighted logrank statistics (Fleming and Harrington, 1991, Counting Process and Survival Analysis. Wiley, New York) and weighted Kaplan-Meier statistics (Pepe and Fleming, 1989. Biometrics 45, 497-507; 1991. J. Roy. Statist. Soc. B 53, 341-352). An illustrated numerical example is reported. Finally, the comparative results of a Monte Carlo error rate and power study for small sample sizes are presented.

AB - In this paper we are concerned with the problem of comparing adjacent ordered treatments in a one-way layout where survival data are subject to random right censorship. Multiple testing procedures based on two-sample statistics, each comparing an individual treatment with the previous one, are proposed for determining the pattern of the treatment effects. The two-sample statistics under consideration are weighted logrank statistics (Fleming and Harrington, 1991, Counting Process and Survival Analysis. Wiley, New York) and weighted Kaplan-Meier statistics (Pepe and Fleming, 1989. Biometrics 45, 497-507; 1991. J. Roy. Statist. Soc. B 53, 341-352). An illustrated numerical example is reported. Finally, the comparative results of a Monte Carlo error rate and power study for small sample sizes are presented.

KW - 62J15

KW - 62N05

KW - Monte Carlo study

KW - Multiple comparisons

KW - One-way layout

KW - Right-censored data

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U2 - 10.1016/s0378-3758(99)00050-6

DO - 10.1016/s0378-3758(99)00050-6

M3 - 期刊論文

AN - SCOPUS:0346687128

VL - 83

SP - 137

EP - 151

JO - Journal of Statistical Planning and Inference

JF - Journal of Statistical Planning and Inference

SN - 0378-3758

IS - 1

ER -

Multiple comparisons between successive treatments for randomly right-censored survival data

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Keywords

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