Microwave assistance of labeling hippuric acid by I-131

Lin Chiang Sherlock Huang, Kou Hung Wu, Pi Wen Ko, Cheng Ying Hsieh, Kuan Chuan Pao, Shih Ching Chou, Fa Kuen Shieh, Radhakrishnan Sureshbabu, Ming Hua Hsu

Research output: Contribution to journalArticlepeer-review

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This work presents a novel approach for labeling hippuric acid with I-131 using microwaves. It utilizes copper(II) acetate as a catalyst of the labeling. The process involves the use of this catalytic copper(II) acetate at low dilutions that were nevertheless sufficient to produce labeled hippuric acid with high radiochemical purity in a short time. Therefore, the novel technique overcomes the limitations of previously reported conventional methods that involve heating.

Original languageEnglish
Pages (from-to)53-57
Number of pages5
JournalApplied Radiation and Isotopes
StatePublished - Jul 2014


  • Copper(II) acetate
  • Hippuric acid
  • Microwave
  • Radiochemical purity


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