Magnetic nanoparticle embedded polydimethylsiloxane layer for reversible microfluidic bonding

Yueh Pu Lee, Chia Wen Tsao

Research output: Chapter in Book/Report/Conference proceedingConference contributionpeer-review

Abstract

In polymer microfluidic fabrication, bonding the polymer replicas with another substrate to create enclosed microfluidic channel is essential for success microchip fabrication. Various microfluidic bonding techniques have been reported for higher bonding strength and better stability. However, the microchip sealing from these bonding techniques are usually permanent which can not be open and re-assemble while accessing the sample inside the microfluidic is required. Polydimethylsiloxane (PDMS) is a widely used polymer material in microfluidic cell analysis due to its non-toxic and gas permeability advantages. In cell research, cells cultured inside the microfluidic device are usually need to remove from the chip for post bioanalysis or identification. Thus, in μTAS 2015, we present using magnetic nanoparticles (MNPs) embedded within the PDMS layer as high bond strength reversible bonding method for microchip applications.

Original languageEnglish
Title of host publicationMicroTAS 2015 - 19th International Conference on Miniaturized Systems for Chemistry and Life Sciences
PublisherChemical and Biological Microsystems Society
Pages1392-1394
Number of pages3
ISBN (Electronic)9780979806483
StatePublished - 2015
Event19th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2015 - Gyeongju, Korea, Republic of
Duration: 25 Oct 201529 Oct 2015

Publication series

NameMicroTAS 2015 - 19th International Conference on Miniaturized Systems for Chemistry and Life Sciences

Conference

Conference19th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2015
Country/TerritoryKorea, Republic of
CityGyeongju
Period25/10/1529/10/15

Keywords

  • Magnetic nanoparticle
  • Polydimethylsiloxane (PDMS)
  • Reversible bonding

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