In this paper, a novel local pattern descriptor generated by the proposed local vector pattern (LVP) in high-order derivative space is presented for face recognition. The proposed vector representation of the referenced pixel is generated to provide the one-dimensional structure of micropatterns. To effectively extract more detailed discriminative information in a given sub-region, the vector of LVP is refined by varying local derivative directions from the nth-order LVP in (n-1)th-order derivative space. The proposed LVP is compared with the existing local pattern descriptors including local binary pattern (LBP), local derivative pattern (LDP), and local tetra pattern (LTrP) to evaluate the performances from input grayscale face images. Extensive experiments conducting on benchmark face image databases, FERET and Extended Yale B, demonstrate that the proposed LVP in high-order derivative space indeed performs much better than LBP, LDP and LTrP for face recognition.