Field-effect transistor biosensors for biomedical applications: Recent advances and future prospects

Cao An Vu, Wen Yih Chen

Research output: Contribution to journalReview articlepeer-review

57 Scopus citations

Abstract

During recent years, field-effect transistor biosensors (Bio-FET) for biomedical applications have experienced a robust development with evolutions in FET characteristics as well as modification of bio-receptor structures. This review initially provides contemplation on this progress by briefly summarizing remarkable studies on two aforementioned aspects. The former includes fabricating unprecedented nanostructures and employing novel materials for FET transducers whereas the latter primarily synthesizes compact molecules as bio-probes (antibody fragments and aptamers). Afterwards, a future perspective on research of FET-biosensors is also predicted depending on current situations as well as its great demand in clinical trials of disease diagnosis. From these points of view, FET-biosensors with infinite advantages are expected to continuously advance as one of the most promising tools for biomedical applications.

Original languageEnglish
Article number4214
JournalSensors (Switzerland)
Volume19
Issue number19
DOIs
StatePublished - 1 Oct 2019

Keywords

  • Antibody
  • Aptamer
  • Biomedical application
  • FET biosensor
  • Field-effect transistor
  • Nanotransducer

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