Direct co-crystal assembly from synthesis to co-crystallization

Hung Lin Lee, Tu Lee

Research output: Contribution to journalArticlepeer-review

13 Scopus citations


Pharmaceutical co-crystals were assembled directly via chemical synthesis by cooling under three new strategies. The screening method for direct co-crystal assembly by a chemical reaction was developed based on liquid-assisted grinding. The ternary phase diagram including a chemical reaction and co-crystallization was established for a 2:1 co-crystal of benzoic acid-sodium benzoate.

Original languageEnglish
Pages (from-to)9002-9006
Number of pages5
Issue number47
StatePublished - 2015


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