Abstract
Pharmaceutical co-crystals were assembled directly via chemical synthesis by cooling under three new strategies. The screening method for direct co-crystal assembly by a chemical reaction was developed based on liquid-assisted grinding. The ternary phase diagram including a chemical reaction and co-crystallization was established for a 2:1 co-crystal of benzoic acid-sodium benzoate.
| Original language | English |
|---|---|
| Pages (from-to) | 9002-9006 |
| Number of pages | 5 |
| Journal | CrystEngComm |
| Volume | 17 |
| Issue number | 47 |
| DOIs | |
| State | Published - 2015 |