Diffuse optical imaging through incorporating structural information into edge-preserving regularization

Liang Yu Chen, Min Cheng Pan, Jhao Ming Yu, Min Chun Pan

Research output: Contribution to journalArticlepeer-review

1 Scopus citations


Diffuse optical imaging (DOI) is emerging as a new functional imaging modality that can be used for breast cancer screening. Due to the ill-posed inverse problem for DOI image reconstruction, regularization is essential to remedy such a drawback. In our previous study, we have successfully implemented edge-preserving regularization into image reconstruction algorithm for improving the reconstructed images. In this study, we incorporate additional anatomical image, which can be obtained from other imaging modality such as mammography or magnetic resonance imaging, although showing no tumor information, into edge-preserving regularization for further improving the reconstructed images. Reconstruction results show that the quality of reconstructed images can be significantly improved.

Original languageEnglish
Article number130
Pages (from-to)1-16
Number of pages16
JournalOptical and Quantum Electronics
Issue number2
StatePublished - 1 Feb 2016


  • A priori information
  • Diffuse optical imaging
  • Edge-preserving regularization


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