Development of nano-metallic catalysts for the single-use, disposable biomedical sensor platform technology

Brandon Bartling, Lei Fang, Lawrence C.S. Chou, Lu Li, Shih Hong Chang, Bing Joe Hwang, Chung Chiun Liu

Research output: Chapter in Book/Report/Conference proceedingConference contributionpeer-review

Abstract

Single use, disposable biosensors for the in vitro detection of biomarkers are important for home care, point-of-care and early stage diagnosis applications. The sensitivity and the repeatability of the biosensor outputs are important, and minimum interference by other components in the test medium is also essential. Enzymatic reactions of the biomarkers producing an electrochemically active species, such as H2O2 and NADH, are often used as a means for the detection of the biomarkers. Nanoparticle metallic catalyst appears to provide enhanced performance of various biosensors. Experimental assessments of many biomarkers, such as glucose, ketone (3β-hydroxybutyrate), total bile acid and others using the nano-particle metallic catalyst have been undertaken. It is also shown that bi-metallic nanoparticles can further enhance the performance of the biosensor. Methods of preparing and testing these of nano-particles will be discussed.

Original languageEnglish
Title of host publication2009 IEEE 3rd International Conference on Nano/Molecular Medicine and Engineering, NANOMED 2009
Pages253-258
Number of pages6
DOIs
StatePublished - 2009
Event2009 IEEE 3rd International Conference on Nano/Molecular Medicine and Engineering, NANOMED 2009 - Tainan, Taiwan
Duration: 18 Oct 200921 Oct 2009

Publication series

Name2009 IEEE 3rd International Conference on Nano/Molecular Medicine and Engineering, NANOMED 2009

Conference

Conference2009 IEEE 3rd International Conference on Nano/Molecular Medicine and Engineering, NANOMED 2009
Country/TerritoryTaiwan
CityTainan
Period18/10/0921/10/09

Keywords

  • Bi-metallic nano-catalyst
  • Biomarkers
  • Disposable biosensor

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