Development of a miniature pCO2 electrode for biomedical applications

N. C. Lai, C. C. Liu, E. G. Brown, M. R. Neuman, W. H. Ko

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5 Scopus citations


A miniature pCO2 electrode for possible CO2 measurement in a biological system was constructed and evaluated. The pCO2 electrode employed a miniature pH glass electrode and the Severinghaus configuration. The electrode was evaluated in both gas and liquid phases. A good linear relation existed between the measured electrode potential of the pCO2 electrode and the logarithm of the CO2 concentration at 20°C in both gas and liquid phases. The temperature dependence of the electrode over the temperature range of 20-60°C was evaluated. From 20 to 40°C, a change of CO2 of 0·15%/°C at a CO2 level of 9·6 mole% was observed. The response time, pCO2 and temperature-hysteresis effects, and long-term stability of the pCO2 electrode were also investigated and discussed.

Original languageEnglish
Pages (from-to)876-882
Number of pages7
JournalMedical & Biological Engineering
Issue number6
StatePublished - Nov 1975


  • In vitro evaluation
  • pCO electrode


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