Determination of perchlorate in river by ion-pair hollow-fiber liquid-phase microextraction coupled with electrospray ionization tandem mass spectrometry

Hsin Chang Chen, Wen Tsen Chen, Wang Hsien Ding

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12 Scopus citations

Abstract

This paper describes the analysis of perchlorate (ClO4 -) in surface water samples by a rapid and reliable ion-pair hollow-fiber liquid-phase microextraction (HF-LPME) method coupled with flow-injection electrospray ionization tandem mass spectrometry (ESI-MS-MS) technique. The effects of the type and concentration of ion-pairing reagents, extraction time, temperature and pH value on the quantitative extraction of perchlorate by ion-pair HF-LPME were investigated and optimized. Di-n-hexyl ammonium acetate (DHAA) was employed to form an extractable ion-pair complex with aqueous perchlorate. The characteristic ions [ClO4-ClO4-DHA]- at m/z 384.6 and 386.7 were observed in the ESI negative-ionization mode. The predominant product ions [ClO4]- at m/z 99 and 101 were used for quantitation and to maximize the detection selectivity and sensitivity. The limit of detection (LOD) was 0.5 μg/L. The reliability and precision of the standard addition method of ion-pair HF-LPME for the determination of trace levels of perchlorate in surface water were demonstrated.

Original languageEnglish
Pages (from-to)442-445
Number of pages4
JournalTalanta
Volume79
Issue number2
DOIs
StatePublished - 15 Jul 2009

Keywords

  • Electrospray tandem mass spectrometry
  • Hollow-fiber liquid-phase microextraction
  • Perchlorate
  • Water analysis

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