Determination of alkylphenol residues in breast and commercial milk by solid-phase extraction and gas chromatography-mass spectrometry

Wei Chun Lin, Shu Li Wang, Chin Yuan Cheng, Wang Hsien Ding

Research output: Contribution to journalArticlepeer-review

27 Scopus citations

Abstract

This study presents a feasible and sensitive method to determine alkylphenol residues (i.e., 4-t-octylphenol (4-t-OP) and the isomers of 4-nonylphenols (4-NPs)) in breast milk samples and commercial cow milk products. The matrix interference associated with the constituents in the milk was reduced by extraction with n-hexane and dilution with 50% methanolic solution (v/v, methanol/water), then followed by the Oasis-HLB SPE extraction. The analytes were determined by a GC-MS system in full-scan and selected ion monitoring modes simultaneously. Limit of quantitation was less than 0.05 ng/g in a 20 g (wet weight) milk sample. The 4-NPs were detected in 19 of the 20 breast milk samples at concentrations ranging from 1.7 to 11.6 ng/g, while 4-t-OP was detected in 8 samples at concentrations ranging from 0.4 to 1.1 ng/g. The 4-NPs were detected in all the testing commercial cow milk products at concentrations ranging from 2.9 to 8.8 ng/g.

Original languageEnglish
Pages (from-to)753-757
Number of pages5
JournalFood Chemistry
Volume114
Issue number2
DOIs
StatePublished - 15 May 2009

Keywords

  • Alkylphenols
  • Breast milk
  • Commercial cow milk
  • GC-MS
  • Solid-phase extraction

Fingerprint

Dive into the research topics of 'Determination of alkylphenol residues in breast and commercial milk by solid-phase extraction and gas chromatography-mass spectrometry'. Together they form a unique fingerprint.

Cite this