Configuration optimization for multi-pinhole micro-SPECT systems by signal detection tasks and system performance evaluations

Ming Wei Lee, Wei Tso Lin, Yi Chun Chen

Research output: Chapter in Book/Report/Conference proceedingConference contributionpeer-review

Abstract

An optimized multi-pinhole aperture can improve the spatial resolution and the sensitivity of pinhole SPECT system simultaneously. In this study, an optimization strategy of the multi-pinhole configuration is proposed, including the preliminary evaluations by geometric analytic models and the system performance evaluations by a simulated human observer, the Fourier crosstalk approach and tomographic image reconstructions. According to the resulting AUC, sensitivity, spatial resolution and reconstructions, a 4-pinhole aperture with 20% multiplexing and 1.52X magnification is the optimized configuration for a micro pinhole-SPECT with a camera with an active area of 49 × 49 mm 2 and a 14-mm diameter spherical field-of-view.

Original languageEnglish
Title of host publication2013 IEEE Nuclear Science Symposium and Medical Imaging Conference, NSS/MIC 2013
PublisherInstitute of Electrical and Electronics Engineers Inc.
ISBN (Print)9781479905348
DOIs
StatePublished - 2013
Event2013 60th IEEE Nuclear Science Symposium and Medical Imaging Conference, NSS/MIC 2013 - Seoul, Korea, Republic of
Duration: 27 Oct 20132 Nov 2013

Publication series

NameIEEE Nuclear Science Symposium Conference Record
ISSN (Print)1095-7863

Conference

Conference2013 60th IEEE Nuclear Science Symposium and Medical Imaging Conference, NSS/MIC 2013
Country/TerritoryKorea, Republic of
CitySeoul
Period27/10/132/11/13

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