Comparisons of diffuse optical imaging between direct-current and amplitude-modulation instrumentations

Liang Yu Chen, Jhao Ming Yu, Min Cheng Pan, Sheng Yih Sun, Chia Cheng Chou, Min Chun Pan

Research output: Contribution to journalArticlepeer-review

6 Scopus citations


Breast tissues like fatty and fibroglandular ones are adipose mainly and possess high scattering nature, so that they diffuse and make the light approximately uniformly distribute over the measured cross-section besides absorbing to reduce the light intensity. Strong cause-and-effect relationships exist between absorption and intensity decay, and between scattering and phase delay as well. Thereby in a diffuse optical imaging system it is a general practice to estimate absorption coefficients from the measured intensity since it reflects most of the absorption property. This study aims to illustrate that both μa and μs images of breast can be reconstructed by only direct-current data reliably to a certain extent. Varied sets of phantom design with assigned absorption/scattering properties for inclusion and background were synthesized and image reconstructed to demonstrate this perspective. Moreover, we employed a slab-type diffuse optical imaging system with a dual-direction direct-current NIR measurement module, where reconstructed images were compared between with and without reflectance NIR data.

Original languageEnglish
Article number139
Pages (from-to)1-11
Number of pages11
JournalOptical and Quantum Electronics
Issue number2
StatePublished - 1 Feb 2016


  • Amplitude-modulation NIR
  • Diffuse optical imaging
  • Direct-current NIR
  • Phantom design
  • Slab-type imaging module


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