Abstract
Crystallization is often performed in solvents or rnixtyres of solvents. Recrystallization by solvent screening is particularly important for the pharmaceutical industry. The authors propose extending initial solvent screening for a single-solvent system to the cocktail solvent screening of binary and ternary solvent mixtures. Solvent mixtures can improve a drug's solubility, provide a higher crystal yield, and allows environmentally harmful solvents to be replaced.
| Original language | English |
|---|---|
| Pages (from-to) | 76-95 |
| Number of pages | 20 |
| Journal | Pharmaceutical Technology |
| Volume | 32 |
| Issue number | 1 |
| State | Published - Jan 2008 |