TY - JOUR
T1 - Chain persistency in single-stranded DNA
AU - Sain, Anirban
AU - Ha, Bae Yeun
AU - Tsao, Heng Kwong
AU - Chen, Jeff Z.Y.
PY - 2004
Y1 - 2004
N2 - We develop a theoretical approach to hairpin-loop formation of single-stranded (ss) DNA by treating the strand as a two-state system in which bases are either “stacked” or “unstacked.” The looping kinetics of ssDNA is shown to be intrinsically different from that of a wormlike chain; it is mainly controlled by stacking-breakage probability, not by the mean curvature of loops, and highly sensitive to the composition of the loop as seen in recent experiments. Our estimate of a stacking energy for poly[Formula presented], [Formula presented], is consistent with known results.
AB - We develop a theoretical approach to hairpin-loop formation of single-stranded (ss) DNA by treating the strand as a two-state system in which bases are either “stacked” or “unstacked.” The looping kinetics of ssDNA is shown to be intrinsically different from that of a wormlike chain; it is mainly controlled by stacking-breakage probability, not by the mean curvature of loops, and highly sensitive to the composition of the loop as seen in recent experiments. Our estimate of a stacking energy for poly[Formula presented], [Formula presented], is consistent with known results.
UR - http://www.scopus.com/inward/record.url?scp=42749102965&partnerID=8YFLogxK
U2 - 10.1103/PhysRevE.69.061913
DO - 10.1103/PhysRevE.69.061913
M3 - 期刊論文
C2 - 15244623
AN - SCOPUS:42749102965
SN - 1063-651X
VL - 69
SP - 4
JO - Physical Review E - Statistical, Nonlinear, and Soft Matter Physics
JF - Physical Review E - Statistical, Nonlinear, and Soft Matter Physics
IS - 6
ER -