Catalytic activity of DNA-Pt complex

Yuki Matsuoka, Toru Onodera, Toshinori Kojima, Akon Higuchi

Research output: Contribution to conferencePaperpeer-review

Abstract

DNA has not been played the role as a biocatalyst in evolutionary history, although RNA and protein function as a biocatalyst. However, recent development of DNA engineering enables to create artificial enzymatic ability of DNA (deoxyribozyme) such as RNA cleavage and DNA modification. We found DNA-Pt complex has enzymatic activity that is similar to peroxidase in this study. We investigated optimal conditions for enzymatic activity of DNA-Pt complex, and compared it with that of horse radish peroxidase. We report that base sequence of DNA, pH and temperature during the reaction affect the enzymatic activity of DNA-Pt complex.

Original languageEnglish
Pages5512
Number of pages1
StatePublished - 2006
Event55th Society of Polymer Science Japan Symposium on Macromolecules - Toyama, Japan
Duration: 20 Sep 200622 Sep 2006

Conference

Conference55th Society of Polymer Science Japan Symposium on Macromolecules
Country/TerritoryJapan
CityToyama
Period20/09/0622/09/06

Keywords

  • Catalyst
  • DNA
  • Enzyme

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