Asymmetric synthesis of bis-tetrahydrofuran cores in annonaceous acetogenins

Chia Hsiu Chen, Ting Chun Kuan, Ke Jhen Lu, Duen Ren Hou

Research output: Contribution to journalArticlepeer-review

4 Scopus citations

Abstract

The bis-THF cores of annonaceous acetogenins were synthesized using (3R,4R)-1,5-hexadiene-3,4-diol (1) as the sole source of carbon atoms. The methylene acetal function was applied as a new linker/tether to facilitate the ring-closing metathesis.

Original languageEnglish
Pages (from-to)3624-3626
Number of pages3
JournalOrganic and Biomolecular Chemistry
Volume8
Issue number16
DOIs
StatePublished - 21 Aug 2010

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