Assessment of a Flow-Measurement Technique for the Printability of Extrusion-Based Bioprinting

Wei Chih Tseng, Chao Yaug Liao, Luc Chassagne, Barthelemy Cagneau

Research output: Contribution to journalArticlepeer-review


Extrusion-based 3D bioprinting is a common application in tissue engineering used to fabricate porous and complex scaffolds for tissue regeneration and repair. Flow-rate measurement can improve printability and reduce the trial-and-error steps needed to optimize printing parameters. This study develops a novel system for flow-rate measurement of chitosan solution based on particle image velocimetry (PIV). The results obtained using PIV are compared with the results obtained using an existing predictive model. In addition, results are double-checked using precision scales to demonstrate the robustness of the PIV method. The experimental results fit the exponential function of the mathematical model (adjusted R-squared = 0.999), and the measured errors of PIV compared to those of the precision scale were within 3%.

Original languageEnglish
Pages (from-to)1716-1723
Number of pages8
JournalIEEE Robotics and Automation Letters
Issue number2
StatePublished - 1 Feb 2024


  • Additive manufacturing
  • bioprinting
  • development and prototyping
  • particle image velocimetry
  • product design


Dive into the research topics of 'Assessment of a Flow-Measurement Technique for the Printability of Extrusion-Based Bioprinting'. Together they form a unique fingerprint.

Cite this