In this study, binary CdSe and ternary Zn0.5Cd0.5Se quantum dots (QDs) with monochromatic light are blended with conventional phosphors and those monochromatic lights of Zn0.5Cd0.5Se QDs are also mixed together and then packaged as remote type. Besides, white light CdSe QD are used alone to fabricate white light-emitting diode (LED). We have demonstrated that the color rendering index (CRI) and luminous efficacy can be improved by blending conventional phosphors with QDs. The Zn0.5Cd0.5Se QDs incorporated with yellow phosphors have better device performance and optical properties. Zn0.5Cd0.5Se QDs with different emission wavelength are blended with each other. The result reveals that mixing ratios and photoluminescence efficiency (PLE) between different colors of QDs are important factors. When white CdSe QD is excited by ultraviolet LED (UV-LED) without mixing multi-colors of phosphor, high CRI can be obtained for CdSe-based white LED.