A simplified application (APP) for the parametric design of screw-plate fixation of bone fractures

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Screw and plate fixation is commonly used to treat bone fractures. A prototype application (APP) for presurgical simulation was developed and validated by comparing it with current analytical approach and other models. In this APP, alternative plate designs and materials to limit the effects of stress shielding could be tested. In addition, the number and position of screws and the gap between bone and plate that achieved acceptable stability were predicted. The fixation stability providing a situation of interfragmentary strain between 2% and 10% is necessary for callus formation. However, improving the fixation stability leads to a stress shielding effect. The simultaneous alleviation of stress shielding and maintenance of stability are important in fracture healing. In this study, the feasibility of creating a specialized APP to evaluate different screw-plate configurations for diaphyseal femoral fractures was investigated. The ultimate goal is to extend this technique to computer-assisted preoperative planning for orthopedic surgery.

Original languageEnglish
Pages (from-to)642-648
Number of pages7
JournalJournal of the Mechanical Behavior of Biomedical Materials
StatePublished - Jan 2018


  • Analytical approach
  • Application (APP)
  • Interfragmentary strain
  • Stress shielding


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