A conceptual synthetic membrane system for active transport

Akon Higuchi, Tsutomu Nakagawa

Research output: Contribution to journalArticlepeer-review


An active transport system with a synthetic membrane has been proposed. The system that effectuates the transport is composed of (1) host molecules of which association constants with a specific substrate can be reversibly changed by photo-irradiation, a change in pH or temperature control, and (2) switching valves on both surfaces of the membrane. This study shows that an active transport can be achieved from successive passive transport steps and the energy for the transport is simply consumed as those for a change in the association constant of the host molecule, for opening and closing of switching valves and for the control of switching valves (i.e., vectorial control). Active transport, which has been considered to be a complicated biological system, is mimicked by a simple hybrid synthetic membrane system (i.e., hybrid-transport theory).

Original languageEnglish
Pages (from-to)274-280
Number of pages7
JournalSen'i Gakkaishi
Issue number6
StatePublished - Oct 1991


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