Study on the Design and Validation for Three-Dimensional Prostrate Optical Tomographical Imaging System(2/2)

Consecutive to our lab study on the diffuse optical tomography, throughthis two-year continual research project the development of DOTtechniques aims at three goals that include (i) the optical scanning andacquisition conforming to the breast profile for prostrate-type breastscreening, (ii) multiple-frequency and square-wave intensity modulatedlight measurement, and (iii) tissue optical-coefficient imagereconstruction for three-dimensional (3D) arbitrary finite-elementmodels. This may bring the developed DOT medical imaging equipment moresuitable to clinical environments for breast tumor screening anddiagnosis. The investigated and developed 3D prostrate-type DOT systemimitates the scheme of breast MRI (BMRI), and thus it can beincorporated with the BMRI to create dual imaging modality. The originalcreative ideas of this project include (i) a moveable source-detectormodule that enables to save the system cost, and acquire more opticalinformation that can enhance the spatial resolution of reconstructedimages, (ii) the multiple- frequency and square-wave intensity modulatedlight measurement that helps, respectively, shorten the time to acquireoptical information, and simultaneously obtain several sets of data ofemitted light intensity and phase lags that benefit the imagereconstruction. In this project, the lab phantom test and clinicaltrials at the Landseed Hospital are arranged to justify the developedtechniques and constructed equipment.