A Computational Study of the Reaction Mechanism of Ketol–Acid Reductoisomerase( II )

蔡, 惠旭 (PI)

Department of Chemistry

Status	Finished
Effective start/end date	1/08/20 → 31/07/21

Keywords

Branched Chain Amino Acid (BCAA) Synthesis
Ketol-Acid Reductoisomerase (KARI)
Ketol Rearrangement
Alkyl Migration
Proton Shuttle
Reaction Mechanism
QM/MM calculation

1 Article

Double Proton Transfer during a Novel Tertiary α-Ketol Rearrangement in Ketol-Acid Reductoisomerase: A Water-Mediated, Metal-Catalyzed, Base-Induced Mechanism
Zhuang, Y. C., Ye, D. S., Weng, S. U. & Tsai, H. H. G., 4 Nov 2021, In: Journal of Physical Chemistry B. 125, 43, p. 11893-11906 14 p.
Research output: Contribution to journal › Article › peer-review
2 Scopus citations